Quantum simulations suggest lithium isotopes could affect biological reactions differently

While lithium has been used as a first-line treatment for the long-term management of bipolar disorder for more than 70 years, scientists still do not fully understand how it produces its therapeutic effects in the brain.In a new study published in PLOS ONE, Surrey researchers used computational chemistry and quantum simulations to investigate whether part of the answer could lie in "nuclear spin"—a quantum property that makes an atom's nucleus behave like a tiny magnet, allowing it to influence nearby electrons and potentially change the outcome of chemical reactions.