Thursday, September 17, 2026
Science

Thinking outside the binding site: Drug molecule makes a square peg fit a round hole

A square peg doesn't fit a round hole. But what if the peg could change the shape of the hole? A newly developed drug molecule can do something surprisingly similar when binding to its target protein, according to a University at Buffalo-led study published Tuesday (Sept. 15) in Angewandte Chemie In...

Thinking outside the binding site: Drug molecule makes a square peg fit a round hole
Image: Phys.org
A square peg doesn't fit a round hole. But what if the peg could change the shape of the hole? A newly developed drug molecule can do something surprisingly similar when binding to its target protein, according to a University at Buffalo-led study published Tuesday (Sept. 15) in Angewandte Chemie International Edition.

Originally published at Phys.org

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