Nanoparticles induce neuroregeneration in Alzheimer's disease models

The adult human brain has limited capacity to repair or regenerate neurons lost to Alzheimer's disease, the most common type of dementia. Existing treatments can slow disease progression but do not reverse cognitive decline. In a study published in the journal Cell Biomaterials on Aug. 26, researchers show that engineered nanoparticles can not only regenerate neurons in human brain organoids but also restore neural circuits and improve cognition in mice.