AI tool predicts how DNA sequences switch on genes across different cell types

Deep learning approaches have transformed how scientists predict the activity and function of DNA sequences in the genome. A new AI tool called Corgi (Context-aware Regulatory Genomics Inference), developed by Martin Vingron's bioinformatics group at the Max Planck Institute for Molecular Genetics allows researchers to predict how the genome behaves across different cell types. The findings could help improve efforts to mimic the activity of cells virtually, with potential applications in basic research and medicine.