Novel generative AI model enables atomic-scale prediction of protein-protein interactions

Proteins are the molecular workhorses of the human body. They perform a vast range of essential functions, from building tissues and transporting molecules to regulating cellular communication and defending against infection. Many medicines, including antibody therapies for cancer and insulin therapy for diabetes, among many others, work by interacting with specific proteins or by replacing proteins that are missing or malfunctioning. Because proteins carry out so many critical biological tasks, the ability to predict and engineer how they interact with one another could open new possibilities for treating disease.