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Cryo-EM imaging reveals how a molecular gate lets bulky proteins pass cell membranes intact

  • June 22, 2026 at 3:00 PM
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Cryo-EM imaging reveals how a molecular gate lets bulky proteins pass cell membranes intact
How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo-EM), Leonid Sazanov and Ziyu Zhao at the Institute of Science and Technology Austria (ISTA) have now uncovered new details about a molecular "gate." Their findings were published in Molecular Cell.

Originally published at Phys.org

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