Single tissue snapshot reveals biological processes unfolding over time

A core challenge in biology is understanding how processes in the body, such as cellular development and regeneration, unfold over long stretches of time, making them notoriously difficult to view at the molecular level. Now, a team led by researchers at Caltech has shown that a single snapshot of a mouse testis is enough to reconstruct the entire weeks-long cycle of sperm production, along with the cell-to-cell coordination that organizes it.