Historical DNA connects 1.3 million living relatives to 17th-century Maryland settlers

As the United States prepares to mark its 250th anniversary, researchers from 23andMe Research Institute, Harvard University, and the Smithsonian Institution have teamed up to study one of the country's founding settlements: St. Mary's City, Maryland. Established in 1634, St. Mary's City was the first English settlement in the colony of Maryland. Despite existing written records and the ability of many present-day Americans to trace their ancestry to the historic city, many gaps remain in our knowledge of this early founder population.