Neutral lipids enable precision control over supramolecular polymerization

The formation of supramolecular polymers within living cells is an emerging strategy for regulating cellular functions, and lipid droplets (LDs) are promising environments for such processes. LDs are cellular organelles composed mainly of neutral lipids, such as triacylglycerols and cholesterol esters, and are deeply involved in cellular functions. However, the self-assembly of supramolecular polymers in neutral lipid-rich environments such as LDs is not well understood.