Tuesday, June 30, 2026
Science

Molecular 'leash' measures force-sensing protein activation at about 15 piconewtons

Researchers at the National University of Singapore (NUS) have built a molecular "leash" to pull directly on a force-sensing protein called Piezo1, and discovered it switches on at about 15 piconewtons, proving that it can be activated by physical tethers, not only by membrane deformation. The study...

Molecular 'leash' measures force-sensing protein activation at about 15 piconewtons
Image: Phys.org
Researchers at the National University of Singapore (NUS) have built a molecular "leash" to pull directly on a force-sensing protein called Piezo1, and discovered it switches on at about 15 piconewtons, proving that it can be activated by physical tethers, not only by membrane deformation. The study is published in the journal Nature Sensors.

Originally published at Phys.org

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