Tuesday, June 30, 2026
Science

Liquid-like histone H1 'glues' nucleosomes, reshaping how DNA compacts

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a dynamic, fluid organization that can still support essential genome functions.

Liquid-like histone H1 'glues' nucleosomes, reshaping how DNA compacts
Image: Phys.org
DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a dynamic, fluid organization that can still support essential genome functions.

Originally published at Phys.org

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