AI-powered tool could speed treatments for antibiotic-resistant bacteria by pinpointing potent peptides

A newly designed AI-powered tool is effective in developing treatments to attack antibiotic-resistant bacteria by breaking down their outer defenses, according to new research from Houston Methodist. The study, published in Nature Communications and led by Eleftherios Mylonakis, M.D., Ph.D., chair, Houston Methodist Charles W. Duncan Jr. Department of Medicine, details how researchers used the tool to identify antimicrobial peptides—small proteins that are part of the body's natural immune system—that effectively targeted bacteria like methicillin-resistant Staphylococcus aureus (MRSA) in lab tests.