New method reveals hidden stereochemical forms of oxidation in antibody drugs
Monoclonal antibodies are among the most widely used biologic medicines, with applications ranging from cancer treatment to autoimmune disease therapy. However, during manufacturing, storage, or transport, antibodies can undergo chemical changes that affect their stability and function. One common m...
Image: Phys.org
Monoclonal antibodies are among the most widely used biologic medicines, with applications ranging from cancer treatment to autoimmune disease therapy. However, during manufacturing, storage, or transport, antibodies can undergo chemical changes that affect their stability and function. One common modification is oxidation of the amino acid methionine.
Originally published at Phys.org
