Tuesday, June 30, 2026
Science

New lipid nanoparticle design improves precision of mRNA vaccine delivery

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to steer the particles toward lymph nodes while reducing off-target delivery to the liver. The advance could make mRNA vaccines more efficient, potentially achieving strong immun...

New lipid nanoparticle design improves precision of mRNA vaccine delivery
Image: Phys.org
Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to steer the particles toward lymph nodes while reducing off-target delivery to the liver. The advance could make mRNA vaccines more efficient, potentially achieving strong immune protection at lower doses.

Originally published at Phys.org

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