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Mining the dark transcriptome: Synthesizing the first potential drug molecules from long noncoding RNA

  • March 10, 2026 at 9:50 PM
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Mining the dark transcriptome: Synthesizing the first potential drug molecules from long noncoding RNA
A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising anti-inflammatory molecules. The team was inspired by advances in the field of messenger RNA (mRNA) and protein replacement therapies. They realized that a similar approach could be used to deliver lncRNA to the body, unlocking a potential new source of drugs.

Originally published at Phys.org

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