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Mapping 3D-super-enhancers with machine learning to pinpoint regulators of cell identity
- March 9, 2026 at 8:00 PM
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Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three dimensions (3D). To better understand how key components of this machinery, such as super-enhancers, regulate genes in this 3D reality, scientists at St. Jude Children's Research Hospital have developed a new algorithm called BOUQUET.
Originally published at Phys.org