How a tryptophan-rich allosteric communication network helps activate a major drug target receptor
A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has revealed how a tryptophan-rich allosteric communication network regulates receptor dynamics and activation of the human adenosine A2A receptor (A2AR), a major G protein-coupled re...
Image: Phys.org
A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has revealed how a tryptophan-rich allosteric communication network regulates receptor dynamics and activation of the human adenosine A2A receptor (A2AR), a major G protein-coupled receptor (GPCR) drug target. The study is published in the Proceedings of the National Academy of Sciences.
Originally published at Phys.org
