AI-powered platform accelerates discovery of new mRNA delivery materials

Integrating AI with advanced robotics to create self-driving labs (SDL) is a promising approach to tackling molecular discovery. A new SDL system, called LUMI-lab, combines large-scale molecular pretraining, active learning, and robotics, and has discovered that brominated lipids, not previously linked to mRNA delivery, enhance the efficiency of getting mRNA inside human cells. The study, led by researchers at the University of Toronto's Leslie Dan Faculty of Pharmacy, is published in Cell.